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. 2013 Apr 19;8(4):e61262. doi: 10.1371/journal.pone.0061262

Figure 6. Prognostic significance of up-regulation of top ranked GACC genes and GAPDH in lung adenocarcinomas.

Figure 6

(A) Director's Challenge cohort with 442 lung adenocarcinomas from caArray for Kaplan-Meier survival analysis. The up-regulation of all selected top ranked GACC gene is associated with poor prognosis. Combination of up-regulation of GAPDH with individual GACC gene improves the prediction power (high GACC gene expression and high GAPDH expression (green line) vs high GACC gene expression alone (blue line)). H = high. L = low. (B) Statistical significance of Kaplan-Meier survival analysis using individual GACC gene as marker (GAPDH−) or combination of GACC gene and GAPDH (GAPDH+) as markers. The table lists p values of chi-square analysis.