Table 1. Top ranked up-regulated GAPDH positively associated genes in NSCLC (correlation coefficient greater than or equal to 0.72).
Gene Title | Symbol | Probe | r value | GO Definition | T/C | p value (t-test) |
triosephosphate isomerase 1 | TPI1 | 213011_s_at | 0.79 | glycolysis | 1.09 | 5.06E-45 |
non-SMC condensinI complex, subunit D2 | NCAPD2 | 201774_s_at | 0.79 | cell cycle | 1.19 | 8.33E-35 |
cell division cycle associated 3 | CDCA3 | 221436_s_at | 0.78 | cell cycle | 1.27 | 3.05E-50 |
forkhead box M1 | FOXM1 | 202580_x_at | 0.77 | cell cycle | 1.54 | 5.89E-49 |
TPX2, microtubule-associated, homolog (Xenopus laevis) | TPX2 | 210052_s_at | 0.76 | cell cycle | 1.62 | 9.96E-57 |
centromere protein A | CENPA | 204962_s_at | 0.75 | centromere protein | 1.59 | 1.29E-47 |
karyopherin alpha 2 (RbAG cohort 1, importin alpha 1) | KPNA2 | 211762_s_at | 0.75 | cell cycle | 1.16 | 4.99E-43 |
glucose-6-phosphate isomerase | GPI | 208308_s_at | 0.75 | glycolysis | 1.11 | 5.81E-44 |
cyclin B2 | CCNB2 | 202705_at | 0.75 | cell cycle | 1.54 | 9.85E-56 |
cell division cycle 20 homolog (S. cerevisiae) | CDC20 | 202870_s_at | 0.75 | cell cycle | 1.66 | 1.09E-57 |
cyclin B1 | CCNB1 | 214710_s_at | 0.74 | cell cycle | 1.61 | 2.68E-57 |
RAD51 associated protein 1 | RAD51AP1 | 204146_at | 0.74 | DNA repair | 1.32 | 9.97E-43 |
solute carrier family 2 (facilitated glucose transporter), member 1 | SLC2A1 | 201250_s_at | 0.74 | glucose transport | 1.45 | 1.02E-46 |
ribonucleotide reductase M2 | RRM2 | 209773_s_at | 0.74 | DNA replication | 1.56 | 2.01E-54 |
aurora kinase B | AURKB | 209464_at | 0.73 | cell cycle | 1.43 | 1.81E-44 |
replication factor C (activator 1) 4, 37kDa | RFC4 | 204023_at | 0.73 | DNA replication | 1.24 | 1.91E-38 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | PSMD2 | 200830_at | 0.73 | cell cycle | 1.06 | 2.69E-26 |
kinesin family member 4A | KIF4A | 218355_at | 0.73 | microtubule-based movement | 1.63 | 1.52E-56 |
baculoviral IAP repeat-containing 5 | BIRC5 | 202095_s_at | 0.73 | cell cycle | 1.62 | 5.74E-56 |
kinesin family member 2C | KIF2C | 209408_at | 0.72 | cell cycle | 1.42 | 6.65E-54 |
cyclin-dependent kinase inhibitor 3 | CDKN3 | 209714_s_at | 0.72 | cell cycle | 1.53 | 2.16E-54 |
ubiquitin-conjugating enzyme E2S | UBE2S | 202779_s_at | 0.72 | cell cycle | 1.17 | 3.38E-29 |
family with sequence similarity 83, member D | FAM83D | 225687_at | 0.72 | cell cycle | 1.40 | 5.67E-35 |
cell division cycle 45 homolog (S. cerevisiae) | CDC45 | 204126_s_at | 0.72 | cell cycle | 1.34 | 5.28E-43 |
cyclin A2 | CCNA2 | 203418_at | 0.72 | cell cycle | 1.62 | 8.53E-49 |
protein regulator of cytokinesis 1 | PRC1 | 218009_s_at | 0.72 | cell cycle | 1.47 | 7.11E-51 |
r = correlation coefficient between GAPDH and current gene expression in NSCLC.
T/C = expression level ratio between cancer and control.