Table 1. Genetic interactions of tna and osa with SUMOylation pathway genes.
Genotype | Number of flies with HWOa | Penetrance (%)a |
+/osa1 | 9/265 | 3 |
+/osa2 | 0/303 | 0 |
+/smt304493 | 0/389 | 0 |
+/lwr4–3 | 1/133 | 1 |
+/lwr5 | 0/297 | 0 |
+/lwr13 | 0/341 | 0 |
+/tna1 | 116/624 | 19 |
tna1/osa1 | 327/334 | 98 |
Df(3L)lxd6/osa1 | 16/115 | 14 |
tna1/osa2 | 140/334 | 42 |
bsmt304493/+; tna1/+ | 44/249 | 18 |
csmt304493/+; tna1/+ | 66/118 | 56 |
lwr4–3/+; tna1/+ | 69/150 | 46 |
lwr5/+; tna1/+ | 71/282 | 25 |
lwr13/+; tna1/+ | 177/343 | 52 |
smt304493/+; osa1/+ | 57/264 | 22 |
smt304493/+; osa2/+ | 0/216 | 0 |
lwr5/+; osa1/+ | 1/147 | 1 |
lwr13/+; osa1/+ | 0/124 | 0 |
lwr5/+; osa2/+ | 0/212 | 0 |
lwr13/+; osa2/+ | 0/256 | 0 |
For expressivity of held-out wing phenotype (HWO) see Fig. 6.
Reciprocal crosses were done were done in all cases with no observed differences except in the crosses with tna1 males and smt304493 femalesb, or with smt304493 males and tna1 femalesc. At least 100 flies were examined for each genotype. Flies that do not present the held-out wing phenotype include tna3, tna5, or tna− deficiencies Df(3L)vin2 and Df(3L)lxd6, osa2, lwr5, lwr4–3, lwr13, smt304493 heterozygous individuals, lwr/+;osa/+, smt304493/+;osa2/+ and all the transheterozygous combinations between tna3, tna5, or Df(3L)vin2 and Df(3L)lxd6 with smt3 and lwr alleles.