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. 2013 Apr 19;8(4):e61571. doi: 10.1371/journal.pone.0061571

Figure 2. Modeling and cryoEM guided molecular dynamics simulations of the interaction between HD5 monomers and vertex proteins of the defensin-sensitive (Ad5.F35) and defensin-resistant (Ad5.PB/GYAR) HAdV chimeras.

Figure 2

(A) Atomic model of the penton base (brown with RGD loops in yellow) and fiber (green) of Ad5.F35 with docked HD5 monomers (red). (B) Similar atomic model of Ad5.PB/GYAR. The smaller model representations in panels A and B show the full length fibers. (C,D) Atomic models of the vertex regions with HD5 monomers shown docked within the cryoEM density.