Skip to main content
. 2013 Apr 19;8(4):e61565. doi: 10.1371/journal.pone.0061565

Table 2. Clinicopathologic features by HER2 status.

Characteristics Categories HER2+ HER2− P value
Median age at diagnosis, years (range) - 43.6 (17.6–74.9) 49.4 (15.8–82.1) 0.094
Ethnic group Chinese (n = 80) 18 (23%) 62 (78%) 0.052
Malays (n = 16) 9 (56%) 7 (44%)
Indians (n = 6) 1 (17%) 5 (83%)
Others (n = 11) 3 (27%) 8 (73%)
Smoking history Non-smoker (n = 29) 9 (31%) 20 (69%) 0.720
Ever-smoker (n = 14) 3 (21%) 11 (79%)
Family history of cancer Negative (n = 39) 12 (31%) 27 (69%) 0.728
Positive (n = 11) 4 (36%) 7 (64%)
Presence of comorbidities No (n = 40) 14 (35%) 26 (65%) 0.267
Yes (n = 68) 17 (25%) 51 (75%)
Stage at diagnosis I (n = 88) 29 (33%) 59 (67%) 0.285
II (n = 5) 0 (-) 5 (100%)
III (n = 11) 2 (18%) 9 (82%)
IV (n = 3) 0 (-) 3 (100%)
Tumour differentiation/grade well (n = 64) 19 (30%) 45 (70%) 0.717
moderate (n = 28) 10 (36%) 18 (64%)
poor (n = 9) 2 (22%) 7 (78%)
Tumour type Mixed borderline (n = 45) 17 (38%) 28 (62%) 0.063
Non-borderline (n = 65) 14 (22%) 51 (78%)
Ovarian surface involvement No (n = 66) 23 (35%) 43 (65%) 0.075
Yes (n = 38) 7 (18%) 31 (82%)
Lymphovascular invasion No (n = 100) 29 (29%) 71 (71%) 0.186
Yes (n = 7) 0 (-) 7 (100%)
Median CA125, U/mL (range) - 37.2 (6.1–415.7) 102.5 (3.0–8812.5) 0.024
Received OGD No (n = 93) 29 (31%) 64 (69%) 0.148
Yes (n = 16) 2 (13%) 14 (88%)
Received colonoscopy No (n = 90) 29 (32%) 61 (68%) 0.057
Yes (n = 19) 2 (11%) 17 (89%)
Received appendectomy No (n = 51) 15 (29%) 36 (71%) 0.833
Yes (n = 58) 16 (28%) 42 (72%)
Received omentectomy No (n = 7) 3 (43%) 4 (57%) 0.400
Yes (n = 103) 28 (27%) 75 (73%)
Received chemotherapy No (n = 57) 18 (32%) 39 (68%) 0.419
Yes (n = 49) 12 (24%) 37 (76%)
Received adjuvant chemotherapy No (n = 69) 19 (28%) 50 (72%) 0.745
Yes (n = 36) 11 (31%) 25 (69%)

Abbreviation: OGD, oesophagogastroduodenoscopy.