Table 2.

Topical delivery systems based on natural polymeric nanoparticles.

Natural Polymeric Nanoparticles	Encapsulated Drug	Target treatment or effect	Particle size	Ref
Gelatin	Pilocarpine HCL	Ophthalmic use	300~500 nm	39
Chitosan	Retinol	Wrinkled skin, acne	50–200 nm	41
Chitosan-TPP	Antisense oligonucleotides	Overexpressed genes	221 nm	42
	Aciclovir	Anti-viral in herpes infections	350–700 nm	43
	Plasmid DNA	Genetic immunization	200–287 nm	44
Lecithin-chitosan	Clobetasol-17-propionate	Antineoplastic, anti-inflammatory	250 nm	45
	Quercetin	Antioxidant, delay UV mediated oxidant	95–168 nm	46