Table 1.
Preterm delivery (%) | Term delivery (%) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Treatment | *n | gd 16–17 | gd 18 | gd 19 | gd 20 | gd 21 | gd 22 | gd 23 | Live/dead pups (%) |
Control | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100/0 |
Stx2 | 8 | 100 | 0 | 0 | 0 | 0 | 0 | 0a | 0/100 |
†Melo control | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100/0 |
†Melo + Stx2 | 8 | 100 | 0 | 0 | 0 | 0 | 0 | 0b | 0/100 |
#AG control | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100/0 |
#AG + Stx2 | 6 | 100 | 0 | 0 | 0 | 0 | 0 | 0c | 0/100 |
#AG+ †Melo control | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100/0 |
#AG+ †Melo + Stx2 | 6 | 0 | 0 | 50 | 17 | 33 | 0 | 0d | 0/100 |
¥ETA control | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100/0 |
¥ETA + Stx2 | 10 | 30 | 30 | 0 | 0 | 10 | 0 | 30 | 30/70 |
#AG + ¥ETA control | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 100 | 100/0 |
#AG + ¥ETA + Stx2 | 10 | 0 | 0 | 0 | 0 | 30 | 0 | 70e | 70/30 |
Meloxicam: 2 μg g−1; #aminoguanidine 100 μg g−1; ¥etanercept 100 μg g−1. *n = number of rats.
aP < 0.005 versus control. bP < 0.005 versus meloxicam control. cP < 0.005 versus aminoguanidine control. dP < 0.005 versus aminoguanidine + meloxicam control. eP < 0.005 versus Stx2. a,b,c,d,eCalculated by Fisher exact test.