Table 5.

Differentiating features of serpiginous choroiditis and tuberculosis-associated multifocal serpiginoid choroiditis (serpiginouslike choroiditis)

	Serpiginous choroiditis	Tuberculosis multifocal serpiginoid choroiditis
History	Born and raised in non-endemic area No history of contact with tuberculosis	Lived in endemic area History of contact with tuberculosis patient
Clinical features	Not multifocal Bilateral Absence of vitritis and anterior chamber reaction or low level of inflammatory reaction Lesions starting from peripapillary area No response to antituberculosis treatment Pigment clumping is located in the borders of healed lesions	Multifocal lesions Usually unilateral Considerable vitreous/anterior chamber inflammatory reaction Lesions starting from macula without peripapillary involvement in the early phases Improved with antituberculosis treatment Pigment clumping usually at the center of lesions
laboratory studies	Negative tuberculin skin test Normal chest x-ray Negative IGRA	Tuberculin skin test usually positive Chest x-ray usually negative IGRA usually positive

IGRA= Interferon gamma release assay