Table 2.
Bivariate analysis of preoperative predictors of major postoperative complications for benign gynecologic surgery (N = 19,439)
| Derivation cohort 2005 to 2008 (n= 9,572) | Validation cohort 2009 (n= 9,867) | p-value | |
|---|---|---|---|
| Age category | .10 | ||
| < 80 years old | 9,368 (97.9) | 9,689 (98.2) | |
| ≥ 80 years old | 204 (2.1) | 178 (1.8) | |
| Race | |||
| White | 5,457 (57.0) | 6,276 (63.6) | 0 |
| Ethnicity | |||
| Hispanic | 1,998 (20.9) | 1316 (13.3) | 0 |
| Hypertension | 2,735 (28.6) | 2,893 (29.3) | .25 |
| Diabetes mellitus | 711 (7.4) | 712 (7.2) | .57 |
| History of CVA with neurologic deficit | 47 (0.49) | 43 (0.44) | .57 |
| Known bleeding disorder | 82 (0.86) | 100 (1.01) | .26 |
| Steroid use for chronic condition | 83 (0.87) | 106 (1.07) | .14 |
| Preoperative systemic infection | |||
| SIRS | 110 (1.15) | 78 (0.79) | .01 |
| Sepsis | 11 (0.11) | 36 (0.36) | 0 |
| Septic Shock | 1 (0.01) | 4 (0.04) | .19 |
| Preoperative blood transfusion > 4 units | 5 (0.05) | 11 (0.11) | .15 |
| Current smoker | 1,819 (19.0) | 1,825 (18.5) | .40 |
| Current pneumonia | 4 (0.04) | 2 (0.02) | .39 |
| Morbid obesity (BMI ≥ 40 kg/m2) | 910 (9.5) | 1014 (10.3) | .07 |
| Prior myocardial infarction within 6 months | 5 (0.05) | 0 | .02 |
| New or exacerbated congestive heart failure | 8 (0.08) | 9 (0.09) | .86 |
| Prior percutaneous coronary intervention | 111 (1.16) | 82 (0.83) | .02 |
| Prior cardiac surgery | 78 (0.81) | 53 (0.54) | .02 |
| Angina within 30 days of surgery | 21 (0.22) | 18 (0.18) | .57 |
| History of peripheral vascular disease (amputation) | 16 (0.17) | 20 (0.2) | .56 |
| Rest pain in lower extremities | 1 (0.01) | 1 (0.01) | .98 |
| New York Heart Class III or IV | 498 (5.2) | 478 (4.8) | .25 |
| Chronic obstructive pulmonary disease | 125 (1.3) | 145 (1.5) | .33 |
| Ventilator dependency | 4 (0.04) | 3 (0.03) | .68 |
| Acute or chronic dialysis | 6 (0.06) | 6 (0.06) | .96 |
| Acute or chronic renal failure | 4 (0.04) | 7 (0.07) | .39 |
| Ascites | 27 (0.28) | 32 (0.32) | .59 |
| Esophageal varicies | 2 (0.02) | 1 (0.01) | .55 |
| Unintentional weight loss of > 10% in last 6 months | 29 (0.3) | 31 (0.31) | .89 |
| Functional status(dependent for ADLs) | 68 (0.71) | 78 (0.79) | .52 |
| Preoperative anemia (hematocrit < 36%) | 1,971 (20.6) | 2,083 (21.1) | .37 |
| ASA score of III, IV, or V | 1,713 (17.9) | 1,819 (18.4) | .33 |
All values listed as n(%)
CVA = cerebrovascular accident; SIRS = systemic inflammatory response syndrome; ADLs = activities of daily living; ASA = American Society of Anesthesiologist