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. 2013 Apr 1;110(16):E1490–E1499. doi: 10.1073/pnas.1219992110

Fig. 4.

Fig. 4.

PBX1 contributes to ETR regulating a unique transcriptional program. (A) Growth assays using two different siRNA targeting PBX1 are represented. Cell number is plotted as a ratio against day 0. (B) Microarray analysis comparing PBX1-dependent expressed genes in MCF7 and LTED cells and the expression levels of the one shared between both cell lines. (C) ChIP-seq for PBX1 around the PBX1-dependent expressed genes shared between MCF7 and LTED cells (±20 kb from transcription start site). Motif search analysis was conducted on the unique and shared PBX1-binding sites. (D) Microarray analysis for the transcription factors recognizing the motifs identified in C. (E) qRT-PCR of PKNOX1 mRNA levels upon siRNA treatment. (F) Growth assays using two different siRNA targeting PKNOX1 are represented. Cell number is plotted as a ratio against day 0.