Table 1.
Mean Tumor Microvessel Density
| Days Post Treatment |
Control a | (n b) | SSL-DXR a | (n b) | p |
|---|---|---|---|---|---|
| 4 | 87.9±2.8 | (41) | 60.8±1.7 | (29) | <0.0001 |
| 7 | 91.1±4.4 | (39) | 84.3c±5.1 | (41) | 0.3151 |
a
Mean microvessel density per field (± standard error of the mean) based on CD31 immunohistochemical staining
b
Number of fields analyzed; each sample set consisted of 3 animals per treatment group and 3 tissue sections analyzed for each animal
c
In SSL-DXR treatment group, the increase in microvessel density from day 4 to day 7 was significant (P<0.001)