Table 3. Haplotype frequencies in the Han Chinese studied.
Amino acids are in the single-letter code.
| SNP | |||||||
|---|---|---|---|---|---|---|---|
| Haplotype* | Original nomenclature† | I11T | V101L | R190W | N192K | A346E | Frequency (%) |
| CH1 | H-6A | T | L | R | N-t‡ | A | 15.9 |
| CH2 | H-11 | T | V | R | N-t | A | 13.2 |
| CH3 | H-1 | T | V | R | K | A | 12.1 |
| CH4 | H-12 | T | V | R | N-t | E | 11.5 |
| CH5 | H-5 | T | L | R | K | A | 10.2 |
| CH6 | H-2 | T | V | W | N-c | A | 8.8 |
| CH7 | H-16 | T | V | R | K | E | 8.1 |
| CH8 | H-19 | T | L | R | N-t | E | 7.9 |
| CH9 | H-17 | T | L | W | N-c | A | 6.5 |
| CH10 | H-20 | T | L | W | N-c | E | 2.0 |
| CH11 | H-8 | I | V | R | N-t | A | 1.3 |
| CH12 | H-4 | I | L | R | N-t | A | 1.3 |
| CH13 | H-6B | T | L | R | N-c | A | 1.0 |
| CH14 | -§ | I | L | R | N-t | E | 0.2 |
| CH15 | H-25A | T | L | R | K | E | 0 |
| CH16 | H-21 | T | V | W | N-c | E | 0 |
| CH17 | H-18 | I | V | W | N-c | A | 0 |
*Each haplotype is defined by the shown linkage of nucleotides in the corresponding row, and each corresponds to the SNPs listed in the top row. Haplotypes were determined with the SHEsis software based on the genotype information from sequencing.
†Original nomenclature follows that of [7,21], and the number represents the ranking of haplotypes in the Caucasian population.
‡SNP that does not change the amino acid.
§Newly discovered haplotype that has not been reported previously.