Skip to main content
. 2013 May;5(5):a012757. doi: 10.1101/cshperspect.a012757

Figure 1.

Figure 1.

Ku and DNA-PKcs. (A) Structural representation of the CTD of human Ku70 (PDB 1JJR) (Zhang et al. 2001). (B) The human Ku70–Ku80 heterodimer bound to DNA (PDB 1JEY) (Walker et al. 2001). (C) The CTD of human Ku80 (PDB 1RW2) (Zhang et al. 2004). (Dashed black lines) Connections between structures. (Light blue) Ku70; (blue) Ku80; (orange) DNA. (D) Low-resolution structure of human DNA-PKcs plus the Ku80 CTD (PDB 3KGV) (Sibanda et al. 2010). (Yellow) Kinase domain, (green) HEAT repeats, (white) “brow,” (blue) putative DBD, and (red) remainder.