Figure 4.

Distribution of gene coverage by fragile sites and by structural cluster regions. Coverage is computed for all biological pathways defined in KEGG and containing at least five genes. Fragile sites cover the 26.38% of chromosomes, and structural cluster regions are set to cover the 26.40%. Structural cluster regions (dotted line) better cover genes in KEGG biological pathways than fragile sites (solid line). See also Supplementary Table S30 and Figure S13.