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. 2013 Feb 22;41(8):4573–4586. doi: 10.1093/nar/gkt113

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Termination efficiencies (k_cat/K_M (M⁻¹ s⁻¹)) of the wt eRF1 and mutant eRF1s at different stop codons. Mutations (A) in the loop 59–68, (B) at positions 33 and 70, (C) at positions 32, 36 and 131, (D) at positions 55, 125 and 129 and (E) at position 71. The termination efficiency of the human wt eRF1 was considered 100%.