Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Mar 6;41(8):4360–4377. doi: 10.1093/nar/gkt157

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by Oxford University Press 2013.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — Examples of genomic loci encoding different immunity systems and containing HEPN and PD-(D/E)xK domains. The genes are depicted as colored block arrows. The HEPN domain is shown by a light green shape with a red outline. The PD-(D/E)xK (RecB-like) domain is shown by a yellow shape with a red outline. HEPN, higher eukaryotes and prokaryotes nucleotide-binding domain, predicted endoribonuclease (54); Sir2, ParB and PD-(D/E)xK, DEDD are nucleases from distinct superfamilies. CRISPR-Cas gene names follow the nomenclature and classification from (18); R-M names follow the nomenclature and classification from (38). (A) HEPN domain associations. (B) PD-(D/E)xK domain associations.