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. 2013 Mar 9;41(8):4481–4494. doi: 10.1093/nar/gkt158

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Distance of genes from the centromere within pericentromeric regions affects the level of HP1a regulation. (A) Correlation plot between the expression ratios in the HP1a mutant versus wild-type and the distance between transcriptional start site (TSS) and centromere (the end coordinates of the gene arms as defined by FlyBase genome release 5.0) within the pericentromeric regions of chromosome 2L and 3L. (B) HP1a binding levels correlated to the distance between TSS and centromere. For both these plots, genes defined as unbound by HP1a were removed. Both y-axis values are on a log₂ scale. The Spearman correlation coefficient was significant for (A) (rs = 0.406, P = 0.013) and (B) (rs = −0.454, P = 0.004).