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. 2013 Apr 12;169(1):10–20. doi: 10.1111/bph.12099

Figure 2.

Figure 2

Cannabimimetic activity of the 3-substituent rimonabant analogues, O-6629 and O-6658, in the mouse tetrad. Mice were treated with O-6629 or O-6658 (s.c.), then assessed in the tetrad tests 1 h later. Locomotor data (A) are expressed as number of beam breaks in a 10 min open field test. Antinociception data (B) are presented as % maximal possible effect (MPE). Hypothermia data (C) are expressed as change in body temperature (pre – post; °C). Catalepsy (D) is expressed as percent time immobile. Data represent the mean (±SEM) of six mice per treatment. Significant differences from vehicle are denoted by * (O-6629) or # (O-6658), P < 0.05.