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Effects of platelet transfusion on prolongation of bleeding time by prasugrel or ticagrelor in rats. Prasugrel and ticagrelor were orally administered 4 h before bleeding time measurements. Platelets (Plt) were infused i.v. 1 h before bleeding time measurements. Bleeding times are shown as the means + SEM (n = 13–14). Plt, platelets; NS, not significant (t-test).
