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. 2013 Apr 12;169(1):90–101. doi: 10.1111/bph.12110

Figure 1.

Figure 1

Carrageenin induces expression of mRNA for IL-33 and ST2 and IL-33 production in the paw skin. Mice received intraplantar (i.pl.) injection of carrageenin (100 μg per paw) or saline (25 μL), and after 2 h samples of paw skin were collected for quantitative (q) PCR analysis of ST2 (panel A) and IL-33 (panel B) mRNA expression or between 0.5 and 5 h for IL-33 determination by ELISA assay (panel C). n = 6 for qPCR and n = 4 for ELISA, representative of two separate experiments. *P < 0.05 compared with the saline group.