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Effect of cannabichromene (CBC, 1 μM) alone and in combination with AM251 (1 μM, CB1 receptor antagonist, A) or rimonabant (SR1, 0.1 μM, CB1 receptor antagonist, B) on [35S]GTPγS binding to hCB1- CHO cell membranes (n = 12–16). CBC was added 30 min after the CB1 antagonists. Symbols represent mean values ± SEM.
