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. 2013 Apr 12;169(1):213–229. doi: 10.1111/bph.12120

Figure 6.

Figure 6

Inhibitory effect of the selective transient receptor potential ankyrin type 1 (TRPA1) agonists carvacrol (0.001–0.1 μM) and cinnamaldehyde (0.001–0.1 μM) (A, B) and of the selective TRPA1 antagonists AP18 (10–20 μM) and HC-030031 (HC, 10–20 μM) (C) on nitrite levels detected in the cell media of macrophages incubated with lipopolysaccharide (LPS, 1 μg·mL−1) for 18 h. Both TRPA1 agonists and antagonists were added to the medium 30 min before LPS challenge. Results are mean ± SEM of two experiments (in triplicates). #P < 0.001 versus control; *P < 0.05, and ***P < 0.001 versus LPS.