Figure 10.

Histological evaluations of inflamed and non-inflamed colons: effect of cannabichromene (CBC). No histological modification was observed in the mucosa and submucosa of control mice (A); mucosal injury induced by dinitrobenzene sulfonic acid (DNBS) administration (B); treatment with CBC reduced colon injury stimulating a regeneration of the glands (C). CBC (1 mg·kg⁻¹) was administered (i.p.) for 2 consecutive days starting 24 h after the inflammatory insult. Histological analysis was performed 3 days after DNBS (150 mg·kg⁻¹, intracolonically). Original magnification ×200. The figure is representative of three experiments.