Table 2.

Anandamide (AEA), 2-arachydonylglycerol (2-AG), palmitoylethanolamide (PEA) and oleoylethanolamide (OEA) levels in cell lysates from macrophages incubated or not with lipopolysaccharide (LPS, 1 μg·mL⁻¹) for 18 h: effect of cannabichromene (CBC, 1 μM, added alone to the cell media or 30 min before LPS challenge)

Drugs	AEA	2-AG	PEA	OEA
Vehicle	0.58 ± 0.13	102.1 ± 15.9	18.4 ± 2.9	9.52 ± 1.4
CBC	0.65 ± 0.22	121.8 ± 38.9	18.3 ± 5.5	7.7 ± 2.4
LPS	1.85 ± 0.55#	122.7 ± 25.9	25.6 ± 6.0	9.73 ± 2.4
LPS + CBC	1.5 ± 0.72	173.9 ± 23.0	33.9 ± 4.2	20.4 ± 2.9*

Results (pmol·mg⁻¹ lipid) are mean ± SEM of three–six experiments. P < 0.01 versus control; *P < 0.05 versus LPS.