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. Author manuscript; available in PMC: 2013 Apr 22.
Published in final edited form as: Dev Dyn. 2012 Jun 23;241(8):1274–1288. doi: 10.1002/dvdy.23817

Figure 11. Graphical Abstract of Slit function during trunk neural crest migration.

Figure 11

Cartoon showing the expression of Slits (red) and Robo receptors (blue) during trunk neural crest development. A Represents a pre-migratory neural crest cells that simultaneously expresses Slit and its Robo receptors, these cells are not motile. B Represents a migrating neural crest cells that expresses Robo receptors but no Slit, these are highly motile cells avoiding dermomyotome (Jia et al., 2005). C Represents neural crest cells expressing Robo receptors stopping by the dorsal aorta after encountering Slit molecules expressed at the entrance of the developing gut, these cells are non-motile, non-epithelial (De Bellard et al., 2003).