Table 1.
Descriptive characteristics of the study population during baseline visit. Numbers show mean, SD, and range.
| Characteristic | Total n (%) or mean (SD, range) |
Male n (%) or mean (SD, range) |
Female n (%) or mean (SD, range) |
| n (%) | 51 (100) | 34 (67) | 17 (33) |
| Age at onset in years, mean (SD, range) |
56.3 (9.2, 36-72) | 55.7 (9.5, 36-71) | 57.3 (8.5, 38-72) |
| Duration of disease (months), mean (SD, range) | 31.7 (24.9, 3-125) | 31.0 (25.6, 3-125) | 32.9 (24.2, 9-104) |
| ALSFRS-R score, mean (SD, range) |
33.0 (8.1, 16-47) | 32.5 (7.5, 19-47) | 34.2 (9.3, 16-44) |
| Weight (kg), mean (SD, range) |
72.5 (14.3, 42-105) | 77.9 (13.3, 57-105) | 61.8 (9.7, 42-84) |
| BMI (kg/m2), mean (SD, range) |
23.6 (3.5, 17-32) | 24.2 (3.5, 19-32) | 22.4 (3.2, 17-29) |
| Vital capacity, % mean (SD, range) |
65.6 (25.4, 14-107) | 60 (25.6, 14-107) | 75.5 (22.6, 23-107) |
| Spinal onset, n (%) | 36 (71) | 26 (77) | 10 (59) |
| Bulbar onset, n (%) | 13 (26) | 6 (18) | 7 (41) |
| Axial onset, n (%) | 2 (4) | 2 (6) | 0 (0) |
| NIV, n (%) | 12 (24) | 9 (27) | 3 (18) |