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. Author manuscript; available in PMC: 2014 Jan 24.
Published in final edited form as: Cancer Genet. 2013 Jan 24;206(0):1–11. doi: 10.1016/j.cancergen.2012.12.004

Figure 2.

Figure 2

Characterization of TMPRSS2 and ERG rearrangement patterns in prostate cancer cell lines determined by the 4-color FISH assay. (A and B) Metaphase FISH and karyogram images from fusion-negative LNCaP; (C and D) Metaphase FISH and karyogram images of fusion-positive VCap. White arrows indicate normal FISH signals, represented as clusters of the 4 probes. Empty arrows with black outline indicate abnormal chromosomes identified during karyotype analysis. Red, green, gold, and aqua arrow or arrow heads highlight positions of FISH signals corresponding to 5’-TMPRSS2, 3’-TMPRSS2, 5’-ERG and 3’-ERG.