Figure 3.
Karyotype analysis and corresponding FISH results on prostate cancer xenografts. LuCaP 58 (A), 96 (B), 23.1 (C), and 35CR (D). Representative interphase FISH images obtained from intact nuclei are shown in (i) of each panel; metaphase FISH images are presented in (ii). Karyogram images are in (iii). Red (R), green (F), gold (G), and aqua (A) arrows in FISH images highlight positions of FISH signals corresponding to 5’-TMPRSS2, 3’-TMPRSS2, 5’-ERG and 3’-ERG. Empty arrows with black outline in karyograms highlight the position of indicated signal(s) on a given chromosome.