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. Author manuscript; available in PMC: 2014 Apr 1.

Published in final edited form as: Crit Care Clin. 2013 Jan 4;29(2):223–238. doi: 10.1016/j.ccc.2012.11.004

Fig. 1 — Algorithm generated by the Brain Trauma Foundation Committee for the first edition of the Guidelines for the Medical Management of Severe Traumatic Brain Injury in Infants, Children, and Adolescents for first-tier therapies (A) and second-tier therapies (B). AFDO₂, arteriovenous difference in oxygen; CBF, cerebral blood flow; CPP, cerebral perfusion pressure; CSF, cerebrospinal fluid; CT, computed tomography; EEG, electroencephalogram; GCS, Glasgow Coma Scale; HOB, head of bed; ICP, intracranial pressure; PaCO₂, partial pressure of carbon dioxide; PRN, as needed; SjO₂, jugular bulb venous oxygen saturation. (From Adelson, PD, Bratton SL, Carney NA, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury. Pediatr Crit Care Med 2003;4(Suppl 3):S65–7; with permission.)

Fig. 1 — Algorithm generated by the Brain Trauma Foundation Committee for the first edition of the Guidelines for the Medical Management of Severe Traumatic Brain Injury in Infants, Children, and Adolescents for first-tier therapies (A) and second-tier therapies (B). AFDO₂, arteriovenous difference in oxygen; CBF, cerebral blood flow; CPP, cerebral perfusion pressure; CSF, cerebrospinal fluid; CT, computed tomography; EEG, electroencephalogram; GCS, Glasgow Coma Scale; HOB, head of bed; ICP, intracranial pressure; PaCO₂, partial pressure of carbon dioxide; PRN, as needed; SjO₂, jugular bulb venous oxygen saturation. (From Adelson, PD, Bratton SL, Carney NA, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury. Pediatr Crit Care Med 2003;4(Suppl 3):S65–7; with permission.)