Figure 6.

Various conformations of villin headpiece drawn from a simulation by Beauchamp et al.¹⁷⁶ The left-most conformation is the native state. Three structures in the middle broadly represent the unfolded state ranging from the partially disordered conformations that still resemble the native state to the significantly extended conformations with low residual secondary content. The right-most structure is a misfolded trap. Such traps lie off the predominant folding pathway.¹⁵⁷