Table 1.
Modified neurological severity score (mNSS) | Points |
---|---|
Motor tests | |
Raising the rat by the tail | 3 |
1 Flexion of forelimb | |
1 Flexion of hind limb | |
1 Head moved more than 10 to the vertical axis within 30 s | |
Walking on the floor (normal = 0; maximum = 3) | 3 |
O Normal walk | |
1 Inability to walk straight | |
2 Circling toward the paretic side | |
3 Falling down to the paretic side | |
Sensory tests | 2 |
1 Placing test (visual and tactile test) | |
2 Proprioceptive test (deep sensation, pushing the paw against the table edge to stimulate limb muscles) | |
Beam balance tests (normal = 0; maximum = 6) | 6 |
0 Balances with steady posture | |
1 Grasps side of beam | |
2 Hugs the beam and one limb falls down from the beam | |
3 Hugs the beam and two limbs fall down from the beam, or spins on beam (>60 s) | |
4 Attempts to balance on the beam but falls off (>40 s) | |
5 Attempts to balance on the beam but falls off (>20 s) | |
6 Falls off: no attempt to balance or hang on to the beam (>20 s) | |
Reflexes absent and abnormal movements | 4 |
1 Pinna reflex (a head shake when the auditory meatus is touched) | |
1 Corneal reflex (an eye blink when the cornea is lightly touched with cotton) | |
1 Startle reflex (a motor response to a brief noise from snapping a clipboard and paper) | |
1 Seizures, mycolonus, myodystony | |
Maximum points | 18 |
One point is awarded for the inability to perform the task or for the lack of a tested reflex: 13-18 = severe injury; 7-12 = moderate injury and 1-6 = mild injury.