Table 1.

Test Categories and Relationship to Breast Cancer Disease Status

Disease Status	Test Category	Genomic Test Example	Conventional Example
Pre-Disease	Predictive Risk Assessment	BRCA1/2 Family History SNP Genotypes	Age, Behavioral factors (e.g., nulliparity)
Asymptomatic Disease	Screening	None	Mammography
Disease Diagnosis	Differential Diagnosis	None	Tumor Histopathology
	Prognosis	HER2 genotype Gene Expression Profile	Estrogen, progesterone receptor
Disease Management & Treatment	Pharmacogenomic	HER2 genotype CYP2D6 genotype	Estrogen, progesterone receptor
	Monitoring	None	Tumor markers (Cancer Antigen CA 15-3, CA 27.29, Carcinoembryonic Antigen)