Table 3. Stratified analyses of the difference hypotensive effects of CCB between KCNH2 (1956,C>T) genotype and gender interaction in EH patients.

variable	men-CC carriers			men-CT/TT carriers			P*(M-CC vs. M-CT/TT)
	2w	4w	6w	2w	4w	6w	2w	4w	6w
N	28	28	27	7	7	7
ΔHR(Bpm)	−0.36±9.3	−1.1±8.5	−2.6±8.0	0.3±6.6	−1.1±10.5	−3.7±9.3	1.000	1.000	1.000
ΔSBP(mmHg)	−13.6±9.9	−13.7±8.7	−15.4±10.6	−27.1±13.1	−18.7±16.8	−28.0±16.7	0.017	1.000	0.070
ΔDBP(mmHg)	−10.4±5.3	−10.7±6.5	−11.3±7.4	−15.0±7.4	−14.0±9.3	−17..4±6.7	0.515	0.989	0.215
ΔPP(mmHg)	−3.2±7.4	−3.1±7.4	−4.0±9.1	−12.3±8.3	−4.8±10.5	−10.6±11.3	0.095	1.000	0.507
ΔMAP(mmHg)	−11.4±6.2	−11.7±6.4	−12.7±7.5	−19.0±8.8	−15.5±11.3	−21.0±9.7	0.066	1.000	0.067

Data expressed as mean ± s.d.

^*P-value adjustment for BMI and age, multiple comparisons with Bonferroni test; ΔHR = change in heart rate, ΔSBP = change in systolic blood pressure, ΔDBP = change in diastolic blood pressure, ΔPP = change in pulse pressure, ΔMAP = change in mean arterial pressure.