Figure 2. Body weight, fat mass and fat free mass in male mice lacking GOAT on a leptin-deficient ob/ob background.

GOAT-ob/ob mice fed standard chow diet display no differences in body weight (a), fat mass (b), or fat free mass (c), compared to ob/ob littermates. However, both leptin-deficient mutants differ significantly in their body adiposity from GOAT-KO and dWT mice, respectively. ** P<0.01 (1-way ANOVA); (n = 5–7).