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. 2013 Apr 22;8(4):e61432. doi: 10.1371/journal.pone.0061432

Table 2. Human/mouse β-Klotho chimeras used to determine Avimer binding site.

Chimera Primary Structure
1 1-F519 (Mouse)::P522-S1044 (Human)
2 1-F521 (Human)::P520-S1043 (Mouse)
3 1-F82 (Human)::P83-G301 (Mouse)::S302-S1044 (Human)
4 1-L193 (Human)::Y194-N415 (Mouse)::G418-S1044 (Human)
5 1-G301 (Human)::S302-F506 (Mouse)::S509-S1044 (Human)
6 1-N417 (Human)::G416-F519 (Mouse)::P522-S1044 (Human)
7 1-F506 (Human)::G507-G632 (Mouse)::L635-S1044 (Human)
8 1-F521 (Human)::P520-A735 (Mouse)::V738-S1044 (Human)
9 1-L633 (Human)::G632-Q849 (Mouse)::D852-S1044 (Human)
10 1-G736 (Human)::A735-S963 (Mouse)::G967-S1044 (Human)