Table 1.
Comparison of patients with and without neoplasm (N = 462)
| Variables | N | Neoplasm
|
p-Values | |
|---|---|---|---|---|
| No (n = 259) | Yes (n = 203) | |||
| Age | 462 | 54.8 ± 16.9 | 59.6 ± 15.3 | 0.002a |
| Race | 461 | n = 258 | n = 203 | 0.0001a |
| Caucasian | 150 (58.1%) | 158 (77.8%) | ||
| African-American | 91 (35.3%) | 39 (19.2%) | ||
| Gender, male | 462 | 133/259 (51.4%) | 120/203 (59.1%) | 0.1 |
| Fever | 453 | 224/252 (88.9%) | 183/201 (91.0%) | 0.45 |
| Days of symptoms, mean ± SD | 444 | 4.77 ± 9.62 | 3.15 ± 4.45 | 0.03a |
| Route | 451 | n = 251 | n = 200 | |
| Healthcare | 81 (32.3%) | 85 (42.5%) | 0.03a | |
| Community-acquired | 170 (67.7%) | 115 (57.5%) | 0.03a | |
| Antibiotic exposure in the last 30 days | 452 | 105/254 (41.3%) | 83/198 (41.9%) | 0.90 |
| Exposure to aminopenicillins | 173 | 2/97 (2.1%) | 8/76 (10.5%) | 0.018a |
| Source | 431 | n = 247 | n = 184 | |
| Urinary | 80 (32.4%) | 30 (16.3%) | 0.0001a | |
| CRBSI | 50 (20.2%) | 22 (12.0%) | 0.02a | |
| Biliary | 8 (3.2%) | 15 (8.2%) | 0.03a | |
| Pneumonia | 10 (4.1%) | 8 (4.4%) | 0.88 | |
| Other/unknown | 99 (40.1%) | 109 (59.2%) | ||
| Surgery in last 30 days | 450 | 79/250 (31.6%) | 74/200 (37.0%) | 0.23 |
| Diabetes mellitus | 462 | 95/259 (36.7%) | 35/203 (17.2%) | 0.0001a |
| Transplant recipient | 460 | 45/258 (17.4%) | 11/202 (5.4%) | 0.0001a |
| Corticosteroids | 459 | 65/256 (25.4%) | 40/203 (19.7%) | 0.15 |
| Septic shock | 300 | 49/178 (27.5%) | 37/122 (30.3%) | 0.6 |
| APACHE II score, mean ± SD | 462 | 12.7 ± 6.4 | 14.3 ± 5.2 | 0.004a |
| WBC count, × 109/l, mean ± SD | 459 | 11.7 ± 7.8 | 10.7 ± 8.6 | 0.005a |
| Platelet count, × 109/l, mean ± SD | 457 | 196.6 ± 119.5 | 174.6 ± 127.1 | 0.0001a |
| Albumin, mean ± SD | 203 | 2.8 ± 0.9 | 2.8 ± 0.8 | 0.77 |
| Creatinine, mean ± SD | 456 | 2.5 ± 2.9 | 1.4 ± 1.3 | 0.0001a |
| Bacteremia | ||||
| Escherichia coli | 455 | 88/254 (34.6%) | 56/201 (27.9%) | 0.12 |
| Klebsiella pneumoniae | 455 | 36/254 (14.2%) | 62/201 (30.8%) | 0.0001a |
| Polymicrobial bacteremia | 410 | 36/235 (15.3%) | 32/175 (18.3%) | 0.42 |
| Enterobacteriaceae + Pseudomonas aeruginosa | 462 | 10/259 (3.9%) | 9/203 (4.4%) | 0.76 |
| Days of effective antibiotic therapy | 397 | 17.4 ± 12.5 | 15.8 ± 9.8 | 0.16 |
| Acute lung injury | 300 | 22/178 (12.4%) | 16/122 (13.1%) | 0.84 |
| Disseminated intravascular coagulation | 300 | 12/178 (6.7%) | 9/122 (7.4%) | 0.83 |
| Mechanical ventilation | 446 | 23/251 (9.2%) | 14/195 (7.2%) | 0.45 |
| Hemodialysis | 460 | 48/257 (18.7%) | 4/203 (2.0%) | 0.0001a |
| Death (all causes) | 453 | 28/252 (11.1%) | 18/201 (9.0%) | 0.45 |
CRBSI, catheter-related blood stream infection; SD, standard deviation; WBC, white blood cell.
a
p-Values < 0.05.