Table 2.
Diagnostic and pathologic characteristics of African American and White women with diagnosis of fibroids at hysterectomy.
| African American (N=225) | White (N=135) | ||||
|---|---|---|---|---|---|
| Mean | (SD) | Mean | (SD) | p-valuea | |
| Uterus size in weeks | 13.1 | (5.1) | 8.9 | (5.5) | <0.0001 |
| Uterus size in grams | 477.0 | (437.4) | 266.9 | (300.2) | <0.0001 |
| Number of fibroids | 9.9 | (8.1) | 4.5 | (4.0) | <0.0001 |
| Number of fibroids (excluding women with imputed values)b |
9.8 | (9.3) | 3.3 | (3.6) | <0.0001 |
| Age at diagnosis of fibroids | 35.5 | (6.66) | 38.6 | (5.95) | <0.0001 |
| Age at surgery | 41.5 | (3.90) | 41.9 | (4.16) | 0.4 |
| Time (years) between diagnosis and surgery |
6.0 | (6.33) | 3.4 | (4.62) | <0.0001 |
| Hemoglobin (g/dL) | 11.8 | (1.7) | 12.8 | (1.5) | <0.0001 |
| N | (%) | N | (%) | p-value | |
| Pre-operative diagnosisc | |||||
| Fibroids/leiomyomas | 201 | (89.3) | 96 | (71.1) | <0.0001 |
| Dysmenorrhea | 36 | (16.0) | 26 | (19.3) | 0.4 |
| Menorrhagia/DUB | 158 | (70.2) | 91 | (67.4) | 0.6 |
| Pelvic pain | 28 | (12.4) | 19 | (14.1) | 0.7 |
| Endometriosis | 1 | (0.4) | 8 | (5.9) | 0.002 |
| Pelvic organ prolapse | 3 | (1.3) | 10 | (7.4) | 0.01 |
| Cervical dysplasia/CIS | 3 | (1.3) | 1 | (0.7) | 1.0 |
| Adenomyosis | 1 | (0.4) | 1 | (0.7) | 1.0 |
| Post-operative diagnosisc | |||||
| Fibroids/leiomyomas | 206 | (91.7) | 100 | (74.1) | <0.0001 |
| Dysmenorrhea | 33 | (14.7) | 26 | (19.3) | 0.3 |
| Menorrhagia/DUB | 151 | (67.1) | 88 | (65.2) | 0.7 |
| Pelvic pain | 27 | (12.0) | 18 | (13.3) | 0.7 |
| Endometriosis | 7 | (3.1) | 20 | (14.8) | <0.0001 |
| Pelvic organ prolapse | 3 | (1.3) | 10 | (7.4) | 0.003 |
| Cervical dysplasia/CIS | 3 | (1.3) | 1 | (0.7) | 1.0 |
| Adenomyosis | 5 | (2.2) | 2 | (1.5) | 0.7 |
| Uterine weight (g) | <0.0001 | ||||
| <100 g | 4 | (1.9) | 18 | (14.2) | |
| 100 – <250g | 80 | (37.9) | 75 | (59.1) | |
| 250 – <500g | 56 | (26.5) | 18 | (14.2) | |
| 500 – <750g | 34 | (16.1) | 10 | (7.9) | |
| 750 – <1000g | 16 | (7.6) | 1 | (0.8) | |
| 1000g – <1500g | 12 | (5.7) | 3 | (2.4) | |
| >1500 g | 9 | (4.3) | 2 | (1.6) | |
| Missing | 14 | 8 | |||
| Uterine size (weeks) | <0.0001 | ||||
| <6 | 9 | (5.0) | 24 | (24.2) | |
| 6 – 10 | 23 | (12.6) | 22 | (22.2) | |
| 11 – 15 | 94 | (51.7) | 42 | (42.4) | |
| 16 – 20 | 36 | (19.8) | 8 | (8.1) | |
| >20 | 20 | (11.0) | 3 | (3.0) | |
| Missing | 43 | 36 | |||
| Number of fibroids | <0.0001 | ||||
| 1 – 4 | 52 | (25.0) | 74 | (61.2) | |
| 5 – 9 | 42 | (20.2) | 23 | (19.0) | |
| 10 – 19 | 87 | (41.8) | 23 | (19.0) | |
| ≥20 | 27 | (13.0) | 1 | (0.8) | |
| Missing | 17 | 14 | |||
| Size of largest fibroid (cm) | <0.0001 | ||||
| ≤2 | 34 | (16.5) | 49 | (40.5) | |
| 2 – <5 | 65 | (31.6) | 38 | (31.4) | |
| 5 – <8 | 61 | (29.6) | 19 | (15.7) | |
| 8 – <10 | 24 | (11.7) | 8 | (6.6) | |
| ≥10 | 22 | (10.7) | 7 | (5.8) | |
| Missing | 19 | 14 | |||
| Number of fibroids AND size of largest fibroid |
<0.0001 | ||||
| <3 AND <2 cm | 13 | (6.4) | 26 | (21.9) | |
| <3 AND 2 to 4.9 cm | 8 | (3.9) | 16 | (13.5) | |
| <3 AND ≥5 cm | 13 | (6.4) | 12 | (10.1) | |
| 3 to 9 AND <2 cm | 12 | (5.9) | 13 | (10.9) | |
| 3 to 9 AND 2–4.9 cm | 21 | (10.3) | 17 | (14.3) | |
| 3 to 9 AND ≥5 cm | 24 | (11.8) | 12 | (10.1) | |
| ≥10 AND <2 cm | 4 | (2.0) | 4 | (3.4) | |
| ≥10 AND 2 to 4.9 cm | 39 | (19.2) | 10 | (8.4) | |
| ≥10 AND ≥5 cm | 69 | (34.0) | 9 | (7.6) | |
| Missing | 22 | 16 | |||
| Location of fibroidc | |||||
| Any submucosal | 92 | (46.5) | 29 | (24.8) | 0.0001 |
| Any intramural | 180 | (90.9) | 104 | (88.9) | 0.6 |
| Any subserosal | 126 | (63.6) | 51 | (43.6) | 0.0005 |
| Pedunculated in cavity | 3 | (1.5) | 2 | (1.7) | 0.9 |
| Pedunculated serosal | 20 | (10.1) | 9 | (7.7) | 0.5 |
| Missing | 27 | 18 | |||
| Location of fibroid | |||||
| Submucosal (SM)only | 5 | (2.5) | 3 | (2.6) | 1.0 |
| Intramural (IM) only | 49 | (24.8) | 54 | (46.1) | <0.0001 |
| Subserosal (SS) only | 6 | (3.0) | 7 | (6.0) | 0.2 |
| Submucosal and intramural | 18 | (9.1) | 9 | (7.7) | 0.7 |
| Submucosal and subserosal | 7 | (3.5) | 3 | (2.6) | 0.7 |
| Intramural and subserosal | 51 | (25.8) | 27 | (23.1) | 0.6 |
| Submucosal, intramural and subserosal |
62 | (31.3) | 14 | (12.0) | 0.0001 |
| Missing | 27 | 18 | |||
a
Continuous variables were compared with student’s t-test, categorical variables were compared with chi-square or Fisher’s exact test.
b
Based on 147 African American and 94 white women.
c
More than one response may have been reported for each woman.