Table 3.
Default Network Regions, Early Life Stress, and N-back Results
| Default Network Region | Effect of ELS a (F, df, p) | Effect of N- back b (F, df, p) | 0-Back c (t, df, p) | 2-Back c (t, df, p) |
|---|---|---|---|---|
| PCC | ||||
| Left | 3.87, 1, 0.07 | 4.19, 1, 0.06 | - | - |
| Right | 5.70, 1, 0.03 | 4.62, 1, 0.05 | 2.01, 17, 0.06 | 2.34, 17, 0.03 |
|
| ||||
| MPFC | ||||
| Left | 9.60, 1, 0.01 | 0.29, 1, 0.60 | 2.75, 17, 0.01 | 2.96, 17, 0.01 |
| Right | 7.37, 1, 0.02 | 0.12, 1, 0.73 | 2.16, 17, 0.05 | 2.78, 17, 0.01 |
|
| ||||
| MFG | ||||
| Left | 8.18, 1, 0.01 | 3.41, 1, 0.08 | 2.32, 17, 0.03 | 2.53, 17, 0.02 |
| Right | 3.12, 1, 0.09 | 3.63, 1, 0.07 | - | - |
|
| ||||
| MTR | ||||
| Left | 0.31, 1, 0.58 | 5.37, 1, 0.03 | - | - |
| Right | 6.60, 1, 0.02 | 3.67, 1, 0.07 | 2.34, 17, 0.03 | 2.26, 17, 0.04 |
ELS = early life stress, PCC = posterior cingulate cortex, MPFC = medial prefrontal cortex, MFG = middle/superior frontal gyrus, MTR = medial temporal region.
a
Results from repeated measures analysis of variance for significant effect of ELS on brain response by region of interest (corrected for multiple comparisons)
b
Results from repeated measures analysis of variance for significant effect of N-back on brain response by region of interest
c
Independent samples t-test of brain response comparing ELS vs. non-ELS groups, shown only in the case of a significant main effect of ELS.