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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Cancer Lett. 2012 Oct 27;340(2):10.1016/j.canlet.2012.10.018. doi: 10.1016/j.canlet.2012.10.018

Figure 4. Single-Cell Sequencing.

Figure 4

Emerging techniques for genome and transcriptome sequencing of single cells permit identification of cancer clones, their lineages, and clonal gene-expression programs in heterogeneous tumors. These technologies have ramifications for future studies of acquired therapeutic resistance and disease progression through tumor evolution.