Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
VEGFR-1 and -2 are expressed differently and exert diverse functions in distinct cell types of the nervous system under physiological conditions. Whereas VEGFR-2 appears to be the main receptor transmitting mitogenic effects in NPCs and differentiated neuronal cells, VEGFR-1 seems to be the main receptor facilitating glial development and survival. Both VEGFRs mediate VEGF-induced neuroprotection and Müller glia cell survival in the adult retina
