Fig 7.

In vivo protection by naproxen treatment of mice infected with influenza A/PR8 virus loads of 50 PFU. (A) Weight change of mice infected with 50 PFU IAV and its uninfected control. (B) Same experiment as described for panel A, with mice treated by intranasal administration of naproxen at a dose of 2 mg/day. Note that both naproxen and oseltamivir (not shown) completely inhibited the weight loss in the infected untreated animals. There were statistical differences between the untreated and treated mice (I-0 and I-2 [A and B]) and the infected and noninfected untreated mice (NI-0 and I-0 [A]).