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. 2013 May;57(5):2005–2009. doi: 10.1128/AAC.01779-12

Table 3.

Food effect assessed by comparing GSK1322322 pharmacokinetic parameters for cohort Ga versus cohort Db

Parameter Value
Point estimate 90% CI CVw (%)c
AUC0–24 (μg · h/ml) 1.01 0.88, 1.17 13.23
AUC0–∞ (μg · h/ml) 1.01 0.87, 1.17 13.25
AUC0–t (μg · h/ml) 1.01 0.88, 1.17 13.23
Cmax (μg/ml) 0.35 0.29, 0.43 18.73
Tmax (h) 2.5d 1.0, 3.5
t1/2 (h) 0.73 0.55, 0.98 26.19
a

An 800-mg dose under the fed condition.

b

An 800-mg dose under the fasted condition.

c

CVw, within-volunteer coefficient of variation.

d

Estimated median difference for Tmax only.