Table 3.
Parameter | Value |
||
---|---|---|---|
Point estimate | 90% CI | CVw (%)c | |
AUC0–24 (μg · h/ml) | 1.01 | 0.88, 1.17 | 13.23 |
AUC0–∞ (μg · h/ml) | 1.01 | 0.87, 1.17 | 13.25 |
AUC0–t (μg · h/ml) | 1.01 | 0.88, 1.17 | 13.23 |
Cmax (μg/ml) | 0.35 | 0.29, 0.43 | 18.73 |
Tmax (h) | 2.5d | 1.0, 3.5 | |
t1/2 (h) | 0.73 | 0.55, 0.98 | 26.19 |
An 800-mg dose under the fed condition.
An 800-mg dose under the fasted condition.
CVw, within-volunteer coefficient of variation.
Estimated median difference for Tmax only.