Table 5.
Clinical efficacies of macrolides, minocycline, and tosufloxacin against MR M. pneumoniae pneumonia
| Treatment group (no. of patients) or parametera | No. (%) of patients whose fever disappeared within 48 h after antibiotic administration | Avg no. of days of fever after antibiotic administration |
|---|---|---|
| AZM (27) | 11 (41) | 3.06b |
| CLR (23) | 11 (48) | 3.15b |
| TFX (62) | 43 (69) | 2.31 |
| MIN (38) | 33 (87) | 1.83 |
| P value for: | ||
| AZM vs CLR | 0.698 | 0.869 |
| AZM vs TFX | 0.017 | 0.062 |
| AZM vs MIN | 0.0002 | 0.002 |
| CLR vs TFX | 0.067 | 0.081 |
| CLR vs MIN | 0.001 | 0.008 |
| TFX vs MIN | 0.047 | 0.152 |
a
AZM, azithromycin; CLR, clarithromycin; MIN, minocycline, TFX, tosufloxacin.
b
Antibiotic changed to TFX or MIN at the second visit for 10 patients in the AZM group and 13 in the CLR group.