Table 14.
Number of clones for specimens from patient W (GT-1b infected), treated BID with 30 mg of DCV
| Mutation(s) | No. of clones at the indicated time pointa |
|||||||
|---|---|---|---|---|---|---|---|---|
| T0-1 | T0-2 | D4-1 | D4-2 | D42-1 | D42-2 | D182-1 | D182-2 | |
| None (WT) | 94 | 93 | 91 | 96 | ||||
| R30Q | 1 | |||||||
| L31I | 15 | |||||||
| L31V | 4 | |||||||
| P32del | 37 | 47 | 5 | |||||
| Y93C | 2 | 1 | 4 | |||||
| L31F-P32del | 1 | |||||||
| L31I-Y93H | 18 | 11 | 45 | 34 | ||||
| L31I-Y93N | 1 | |||||||
| L31I-Y93R | 4 | |||||||
| L31V-Y93H | 15 | 2 | 4 | |||||
| P32del-Y93H | 25 | 18 | ||||||
| Total clones | 96 | 95 | 95 | 96 | 95 | 95 | 48 | 48 |
a
Two different primer sets (-1 and -2) were used for the same specimen derived from each time point indicated.