Table 6.
Mutation(s) | No. of clones at the indicated time point |
||||
---|---|---|---|---|---|
T0 | T24 | D14 | D15 | D182 | |
None (WT) | 87 | 16 | 1 | 5 | 2 |
M28T | 3 | ||||
M28V | 2 | ||||
Q30E | 10 | 2 | |||
Q30H | 23 | 13 | 5 | 13 | |
Q30K | 4 | 11 | |||
Q30R | 1 | 28 | 19 | 19 | 6 |
L31M | 4 | 2 | 5 | ||
L31V | 1 | 44 | 81 | 119 | |
H58D | 4 | 3 | |||
Y93C | 2 | ||||
Y93H | 2 | 9 | 5 | 19 | |
Y93N | 1 | ||||
M28T-Y93C | 1 | ||||
Q30H-L31P | 1 | ||||
Q30H-L31V | 2 | ||||
Q30R-L31M | 1 | 1 | |||
Q30R-H58D | 2 | ||||
Q30R-Y93H | 1 | 2 | |||
Q30R-Y93N | 1 | ||||
L31V-H58L | 1 | ||||
L31V-H58P | 1 | ||||
L31V-Y93H | 6 | ||||
Q30H-L31P-Y93H | 1 | ||||
Total clones | 95 | 86 | 109 | 150 | 152 |