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Area under the bacterial killing curves (AUBC) of single drugs and 2- and 3-drug combinations against 12 KPC K. pneumoniae isolates. The median AUBC was significantly lower for colistin-doripenem-ertapenem than colistin with a carbapenem (colistin-ertapenem, P = 0.0002; colistin-doripenem, P = 0.05) and colistin only (P < 0.0001).
