Table 2.
Compound no. | Name | % secretiona (mean ± SD) |
---|---|---|
1 | Curvulin | 67.2 ± 3.6 |
2 | C1 | 58.3 ± 14.5 |
3 | C2 | 50.6 ± 8.2 |
4 | C3 | 35.2 ± 12.1 |
5 | Secocurvularin | 13.3 ± 4.1 |
6 | C5 | 10.5 ± 2.4 |
7 | Csn-B | 2.1 ± 1.4 |
8 | C8 | 16.2 ± 6.7 |
9 | E0 | 104.2 ± 12.6 |
10 | E1 | 99.5 ± 21.4 |
11 | E2 | 101.5 ± 3.4 |
12 | E3 | 80.2 ± 5.5 |
13 | E4 | 53.5 ± 16.7 |
14 | E5 | 64.5 ± 6.5 |
15 | E6 | 28.3 ± 10.8 |
16 | A2 | 60.3 ± 6.4 |
17 | A3 | 96.3 ± 3.7 |
18 | A4 | 92.5 ± 9.6 |
19 | A5 | 70.3 ± 19.0 |
20 | INP0403 | 7.1 ± 1.3 |
% secretion: the percentage of SipC protein from culture supernatants treated by different compounds was calculated by Western blots compared with DMSO control for three independent replicates, and standard deviations are shown. Compounds were tested at a final concentration of 100 μM.