Increased local expression of IL-23 and CCL20 in the setting of AR. A, Immunohistochemical staining of CCL20 in murine nasal tissues. B-D, Number of CCL20+ cells (Fig 5, B) and relative mRNA expression of IL-23p19 (Fig 5, C) and IL-23p40 (Fig 5, D) in murine nasal mucosa. *P < .05 and **P < .01 (n = 8-10 mice per group). E and F, Relative mRNA expression of CCL20 (Fig 5, E) and IL-23p19 (Fig 5, F) in the nasal mucosa of control subjects (n = 12) and patients with AR (n = 12). **P < .01. G, CC10 inhibits CCL20 mRNA expression in BEAS-2B cells. *P < .05 compared with medium controls, #P < .05 compared with the corresponding condition with CC10 treatment (n = 3-5).