Figure 3.

Serum ferritin levels in patients with deletional hemoglobin H disease (HbH) and hemoglobin H–Constant Spring disease (HCS) and correlation with liver iron concentration. The trend for ferritin levels according to age on the basis of linear regression (dashed line) increases after the age of 18 years in patients with HbH (A), and increases from birth to the age of 30 years in those with HCS (B). A significant correlation between the serum ferritin level and liver iron concentration is shown in patients with HbH and HCS (C), with the dashed line indicating the linear regression of liver iron concentration as compared with ferritin. (From Lal et al. 2011; reprinted, with permission, © The Massachusetts Medical Society.)