Table 4.
Hematology of red blood cell indices in midpregnancy fetuses
| Parameter (mean ± SD) | Normal (n = 22) | α1 traita (n = 40) | Hb Bart’s hydrops (n = 26) | P |
|---|---|---|---|---|
| Gestational age (wk) | 18.9 + 9.5 | 18.6 + 7.9 | 18.8 + 8.8 | .422 |
| Hb level (g/dL) | 11.34 ± 0.83 | 10.42 ± 0.91 | 6.4 ± 1.64 | <.001 |
| MCV (fL) | 123.40 ± 7.76 | 105.95 ± 7.35 | 96.26 ± 8.19 | <.001 |
| MCH (pg) | 41.39 ± 3.35 | 33.71 ± 2.74 | 26.23 ± 2.6 | <.001 |
| MCHC (g/dL) | 33.44 ± 1.3 | 31.81 ± 1.09 | 27.29 ± 1.78 | .001 |
ANOVA test before post hoc multiple comparisons (fetuses, n = 86). (Data from Srisupundit et al. 2008.)
Hb, hemoglobin; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration.
aα1 trait is the heterozygous state for α0-thalassemia (–/αα).